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The Read

Nkarta’s stock rallied over 5% after Q4 2025 earnings when it announced a strategic autoimmune focus and higher NKX019 dosing, but then plunged about 20% after Q1 2026 earnings due to lack of near-term clinical catalysts.
Oct 15, 2026 — NKX019 (Ntrust-2) Final Cohort Data
Chart by TradingView

The schedule

  • Thu15Oct

    Final cohort data readout for the Ntrust-2 trial evaluating NKX019.

  • Tue8Dec

    Potential strategic partnership or pipeline reprioritization announcement.

  • Tue22Dec

    Phase 1/2 dose-expansion data presentation for NKX019 in lupus nephritis.

  • Tue9Feb

    Q3 2026 earnings release and regulatory pathway update.

  • Sun14Feb

    Q4 2026 earnings release and full-year 2027 clinical outlook.

  • Tue11May

    Q1 2027 earnings release and early execution update on pivotal trials.

Past

  • Tue11Aug

    Actual outcome: Mixed · $2.33 at outcome

    Nkarta reported Q2 2026 EPS of -$0.37, exactly in line with consensus estimates. The company's updates regarding its cash runway and registrational trial enrollment provided no significant surprises to alter investor sentiment. Consequently, the stock remained flat as the market digested the anticipated progress without a clear directional catalyst.

    Q2 2026 earnings release focusing on cash runway and trial enrollment updates.

  • Fri10Jul

    Actual outcome: Bear · $2.65 at outcome

    NKTX executed a dilutive secondary equity offering to shore up its exhausted balance sheet. The market reacted negatively to the resulting shareholder dilution and ongoing cash burn concerns, driving the stock down 10.8% by the outcome date and eventually pushing it below the bear floor.

    Potential dilutive capital raise to shore up NKTX's exhausted balance sheet.

  • Tue12May

    Actual outcome: Bull · $2.68 at outcome

    Nkarta reported its first-quarter 2026 results, highlighting ongoing enrollment at the 4 billion cell dose level for its Ntrust-1 and Ntrust-2 autoimmune trials alongside a new regulatory agreement supporting outpatient dosing in community-based settings. The stock reacted positively because the shift to outpatient dosing significantly reduces patient burden, expanding the therapy's potential accessibility and commercial viability. Furthermore, the confirmation that initial clinical data from both trials will be presented at a medical meeting later in the year provided investors with a clear, near-term catalyst.

    External class-effect catalyst as peer companies report data on CAR-T and CAR-NK approaches in autoimmune indications.

  • Tue12May

    Actual outcome: Bear · $2.64 at outcome

    Nkarta reported Q1 2026 EPS of -$0.37, which was exactly in-line with consensus estimates. However, the corporate update lacked immediate clinical catalysts, noting only ongoing enrollment for its Ntrust trials and pushing expectations for initial data to a future medical meeting later in 2026. This absence of near-term upside drivers disappointed investors, causing the stock to drop 19.5% and break below the bear floor shortly after the release.

    Q1 2026 earnings report and pipeline update.

  • Wed25Mar

    Actual outcome: Mixed · $2.19 at outcome

    Nkarta reported in-line Q4 2025 EPS of -$0.37 and announced a strategic workforce reorganization to add autoimmune clinical expertise. The company also revealed plans to escalate doses of its CAR-NK therapy NKX019 to a 12 billion cell regimen aimed at deepening B-cell depletion, which encouraged investors and ultimately drove the stock well past the bull target in the following weeks.

    Release of fiscal year 2025 results and management commentary on 2026 cash runway.